Cart
sales@molnova.com
C5-benzyl SAHA
CAS No. 2115700-64-4
C5-benzyl SAHA ( —— )
Catalog No. M13367 CAS No. 2115700-64-4
C5-benzyl SAHA is a C5-modified SAHA analog that displays dual selectivity to HDAC.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameC5-benzyl SAHA
-
NoteResearch use only, not for human use.
-
Brief DescriptionC5-benzyl SAHA is a C5-modified SAHA analog that displays dual selectivity to HDAC.
-
DescriptionC5-benzyl SAHA is a C5-modified SAHA analog that displays dual selectivity to HDAC6 (IC50=0.27 uM) and HDAC8 (IC50=0.38 uM) over HDAC 1, 2, and 3 (IC50=2.9-5.8 uM); dose dependently and selectively increases in levels of acetyl-α-tubulin in U937 leukemia cells.
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
RecptorHDAC
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2115700-64-4
-
Formula Weight354.45
-
Molecular FormulaC21H26N2O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name4-benzyl-N8-hydroxy-N1-phenyloctanediamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Negmeldin AT, et al. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3254-3258.
molnova catalog
related products
-
Sodium Phenylbutyrat...
Sodium Phenylbutyrate is a transcriptional regulators that act by altering chromatin structure via the modulation of HDAC activity.
-
Merck60
Merck60 (BRD 6929, Compound-60)is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively.
-
Givinostat
Givinostat or gavinostat, aslo known as ITF2357, is a potent and orally active histone deacetylase inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities.
